AmoyDx® HANDLE HRR NGS Panel

NGS Assay - CE-IVD
Breast cancer/ Ovarian cancer/ Prostate cancer/ Pancreatic cancer

The AmoyDx® HANDLE HRR NGS Panel facilitates the detection of somatic and germline variants across 27 genes within the Homologous Recombination Repair (HRR) pathway, along with 5 tumor driver genes.

27 HRR genes: All coding regions, exon-intron boundaries of AR, ATM, ATR, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CDK12, CHEK1, CHEK2, ESR1, FANCA, FANCL, HDAC2, HOXB13, MRE11, NBN, PALB2, PPP2R2A, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, STK11 and TP53. 5 driver genes (BRAF, ERBB2, KRAS, NRAS, PIK3CA): hotspot regions

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